Gene | Loci of mutations | Odd ratio | 95% CI | p-value |
inhA | No mutation inhA 14 inhA 81 inhA 84 inhA 86 inhA 114 | 1.00 0.66 3.00 1.23 0.60 8.12 | Reference 0.10 - 4.55 0.14 - 65.52 0.09 - 17.00 0.04 - 8.19 1.17 - 56.10 | - 0.676 0.484 0.876 0.702 0.034 |
ahpC | No mutation ahpC 10 ahpC 12 ahpC 76 | 1.00 1.88 1.88 0.51 | Reference 0.17 - 20.11 0.17 - 20.11 0.05 - 5.31 | - 0.602 0.602 0.577 |
rpoB | No mutation rpoB 445 rpoB 450 rpoB 483 rpoB 490 rpoB 507 rpoB 508 | 1.00 20.64 0.54 1.51 0.23 3.53 12.23 | Reference 1.44 - 295.42 0.03 - 8.35 0.08 - 29.17 0.01 - 4.59 0.30 - 41.70 0.20 - 757.35 | - 0.026 0.659 0.783 0.336 0.317 0.234 |
rrs | No mutation rrs 223 rrs 241 rrs 408 rrs 414 rrs 512 | 1.00 1.85 0.70 2.17 6.90 3.68 | Reference 0.15 - 22.38 0.01 - 32.78 0.28 - 16.60 0.77 - 61.89 0.17 - 77.73 | - 0.628 0.856 0.456 0.084 0.402 |
Minor side effect | No minor side effect Minor side effect | 1.00 0.14 | Reference 0.15 - 22.38 | - 0.020 |