Gene mutation codon

MDR-TB

n (%)

Pre-XDR

or

XDR-TB

n (%)

Total

p-value

rpoB

No mutation

rpoB 445

rpoB 450

rpoB 464

rpoB 483

rpoB 490

rpoB 493

rpoB 507

rpoB 508

4 (16.7)

3 (12.5)

5 (20.8)

6 (25.0)

2 (8.3)

5 (20.8)

2 (8.3)

7 (29.2)

8 (33.3)

2 (20.0)

5 (50.0)

1 (10.0)

0 (0.0)

2 (20.0)

2 (20.0)

2 (20.0)

2 (20.0)

1 (10.0)

6 (17.7)

8 (23.5)

6 (17.7)

6 (17.7)

4 (11.8)

7 (20.6)

4 (11.8)

9 (26.5)

9 (26.5)

0.584

0.031

0.416

0.100

0.334

0.670

0.334

0.462

0.165