Gene mutation codon | MDR-TB n (%) | Pre-XDR or XDR-TB n (%) | Total | p-value |
katG |
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No mutation katG 315 katG 320 katG 300 katG 302 katG 314 katG 308 katG 299 katG 340 katG 343 katG 310 katG 312 | 10 (41.7) 10 (41.7) 1 (4.2) 0 (0.0) 0 (0.0) 1 (4.2) 1 (4.2) 0 (0.0) 3 (12.5) 5 (20.8) 1 (4.2) 1 (4.2) | 4 (40.0) 2 (20.0) 0 (0.0) 1 (10.0) 0 (0.0) 0 (0.0) 2 (20.0) 1 (10.0) 1 (10.0) 2 (20.0) 2 (20.0) 3 (30.0) | 14 (41.2) 12 (35.3) 1 (2.9) 1 (2.9) 1 (2.9) 1 (2.9) 3 (8.8) 1 (2.9) 4 (11.8) 7 (20.6) 3 (8.8) 4 (11.8) | 0.618 0.211 0.706 0.294 0.294 0.706 0.201 0.294 0.666 0.670 0.201 0.067 |
InhA |
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No mutation inhA 14 inhA 25 inhA 78 inhA 81 inhA 84 inhA 86 inhA 94 inhA 114 | 5 (20.8) 8 (33.3) 1 (4.2) 5 (20.8) 5 (20.8) 6 (25.0) 6 (25.0) 3 (12.5) 5 (20.8) | 2 (20.0) 3 (30.0) 0 (0.0) 3 (30.0) 2 (20.0) 3 (30.0) 2 (20.0) 0 (0.0) 6 (60.0) | 7 (20.6) 11 (32.4) 1 (2.9) 8 (23.5) 7 (20.6) 9 (26.5) 8 (25.5) 3 (8.8) 11 (32.4) | 0.670 0.591 0.706 0.435 0.670 0.538 0.565 0.338 0.036 |
ahpC |
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No mutation ahpC 10 ahpC 12 ahpC 20 ahpC 22 ahpC 75 ahpC 76 | 14 (58.3) 2 (8.3) 2 (8.3) 3 (12.5) 2 (8.3) 6 (25.0) 5 (20.8) | 7 (70.0) 2 (20.0) 2 (20.0) 1 (10.0) 1 (10.0) 1 (10.0) 1 (10.0) | 21 (61.8) 4 (11.8) 4 (11.8) 4 (11.8) 3 (8.8) 7 (20.6) 6 (17.7) | 0.406 0.334 0.334 0.666 0.662 0.315 0.416 |