| Day Cream (study design „protective”) | ||||
| t0 (day 2) | t0 - t1 | t1 (day 16) | t2 (day 17) | |
| Preparation |
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| Informed consent | X |
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| In-/Exclusion criteria | X |
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| Parameter |
| |||
| Biophysical measurements (TEWL, SC hydration, ss-pH) | X | X | X | |
| SC lipid matrix analysis by Lipbarvis® (nICCL) | X | X | ||
| Test site 1: test product application (twice daily, 14 days) | X* | X | X |
|
| Test site 2: not product-treated | X | X | X |
|
| Cigarette smoke exposure on both test sites (30 min) | X |
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