Weeks

DLQI score

p-value

Mean ± SD

^*Pair 1

0

2

20.04 ± 4.68

14.00 ± 6.95

<0.0000001

Pair 2

2

6

14.00 ± 6.95

7.96 ± 5.91

<0.000001

Pair 3

6

14

7.96 ± 5.91

4.52 ± 4.82

<0.001

Pair 4

14

22

4.52 ± 4.82

3.87 ± 5.60

<0.2072 ^**(N.S)