Primary screening (% of residual activity at 10 mM and 1 mM)
Compound	Conc. (mM)	CDK5/ p25	CDK9/ cyclin T	CK1e	GSK3b	Haspin	PIM1	CLK1	DYRK1A
5a	10	≥100	96	60	79	55	96	80	71
5a	1	98	76	65	82	91	84	88	99
5b	10	98	84	78	85	68	97	78	≥100
5b	1	95	61	52	90	≥100	99	87	85
5c	10	98	72	63	78	60	72	90	90
5c	1	94	57	44	72	45	81	80	58
5d	10	91	51	38	65	34	79	81	82
5d	1	94	54	57	82	51	78	75	57
6a	10	86	62	58	66	46	52	51	34
6a	1	≥100	60	63	74	67	84	83	71
6b	10	76	57	47	71	53	68	74	65
6b	1	86	50	42	65	90	92	75	67
6c	10	80	43	46	55	38	72	81	74
6c	1	89	54	59	64	71	80	71	78
6d	10	87	38	39	31	31	76	61	≥ 100
6d	1	89	63	67	78	66	77	71	88