δ-hemolysin and its variants

Characteristics of native state

pH 2

pH 7

G = H

G = P

G = H

G = P

δ-hemolysin

–12 (2160)

[51] {1507-1931}

–11 (7552)

[106] {1433-1839}

–12 (2160)

[58] {1496-1926}

–11 (7552)

[120] {1422-1830}

Variant position 3, Q→A

–12 (6328)

[131] {1306-1931}

–12 (760)

[7] {1517-1641}

–12 (6328)

[164]{1306-1962}

–12 (760)

[23] {1483-1859}

Variant positions 10 - 12, GDL→VEF

–13 (744)

[23] {1586-1949}

–13 (744)

[23] {1586-1949}

–12 (2160)

[55] {1578-2008}

–12 (2160)

[55] {1578-2008}

Variant position 15, W→L

–12 (2160)

[53] {1523-1947}

–11 (7552)

[94] {1449-1866}

–12 (2160)

[58] {1496-1926}

–11 (7552)

[120] {1422-1830}

Variant positions 17 - 18, ID→AE

–13 (696)

[17] {1467-1770}

–13 (264)

[6] {1575-1770}

–12 (2160)

[57] {1403-1810}

–11 (7552)

[136] {1329-1721}

Variant position 21, N→E

–12 (7312)

[150] {1310-1931}

–12 (432)

[16] {1426-1855}

–12 (2160)

[58] {1496-1926}

–11 (7552)

[120] {1422-1830}

Variant position 24, T→I

–12 (2160)

[45] {1660-2018}

–11 (7552)

[105] {1586-1989}

–12 (2160)

[52] {1645-2012}

–11 (7552)

[116] {1571-1997}