At pH 2

At pH 7

Very Hydrophobic

L

100

F

100

I

100

I

99

F

92

W

97

W

84

L

97

V

79

V

76

M

74

M

74

Hydrophobic

C

52

Y

63

Y

49

C

49

A

47

A

41

Neutral

T

13

T

13

E

8

H

8

G

0

G

0

S

–7

S

–5

Q

–18

Q

–10

D

–18

Hydrophilic

R

–26

R

–14

K

–37

K

–23

N

–41

N

–28

H

–42

E

–31

P

–46

P

–46 (used pH 2)

D

–55