Treatment beginning time after reperfusion, h

Group

Cerebral infarct volume, mm³

Cerebral infarct volume reduction, %

Experiment 1

6

MCAO

696 (412 - 1163)

70%*

MCAO + GK-2

203 (110 - 515)*

Experiment 2

8

MCAO

555 (361 - 732)

62%*

MCAO + GK-2

214 (103 - 383)*

Experiment 3

24

MCAO

682 (614 - 938)

18%#

MCAO + GK-2

565 (305 - 871)#