Case

Author

Gender

Age Smoking (years)

History

Histology

TNM staging

Mutated genes

Treatment

Response

PFS (month)

Os (month)

1

Chen, et al.

NA

NA

No

Adenocarcinoma

NA

RO51 EGFR (19del)

Gefitinib

PR

NA

NA

2

Chen, et al.

NA

NA

No

Adenocarcinoma

NA

RO51 EGFR(19del)

Gefitinib

PR

NA

NA

3

Chen, et al.

NA

NA

No

Adenocarcinoma

NA

ROS1 EGFR(19del)

NA

NA

NA

NA

4

Chen, et al.

NA

NA

No

Adenocarcinoma

NA

ROS1 EGFR (20-ins)

NA

NA

NA

NA

5

Mao, et al.

Female

55

No

Adenocarcinoma

NA

CD74-ROS1 EGFR(19del)

Crizotinib

5D

7.0

15.4

6

Mao, et al.

Male

45

No

Adenocarcinoma

NA

EZR-ROS1 EGFR (19del)

Crizatinib

PR

23.0

35

7

Mao, et al.

Male

59

No

Adenocarcinoma

NA

CD74-ROS1 EGFR (L858R)

Crizatinib

PD

2.0

24

8

Zhu, et al.

Female

50

No

Adenocarcinoma with sarcomatoid differentiation

T2aNOMO stage Ib

CD74-ROS1 EGFR(L858R)

Postoperative chemotherapy

RO resectiona

NA

NA

9

present case

Female

64

No

Adenocarcinoma with sarcomatoid differentiation

T2N2MO stage IIIa

SLC34A2-ROS1 EGFR ARIDIA NFKBIA

Postoperative chemotherapy and radiotherapy

RO resectiona

NA

NA