Drug

Dose/Route

Day(s)

ABVD Protocol:

Doxorubicin

Bleomycin

Vinblastin

Decarbazine

(repeat every 28 days)

25 mg/m² IV

10 mg/m² IV

6 mg/m² IV

375 mg/m² IV

d1, 15

d1, 15

d1, 15

d1, 15

COEP Protocol:

Cyclophosphamide

Vincristine (Oncovin)

Etoposide*

Prednisone

(repeat every 28 days)

800 mg/m² IV

1.5 mg/m² IV

60 mg/m² IV

40 mg/m²/day PO

d1, 15

d1, 15

d1, 15

d1, 15 then gradual withdrawal