ypN0

21

(52.5%)

9

(42.9%)

12

(63.2%)

0.19§

ypN1

18

(45%)

12

(57.1%)

6

(31.6%)

ypN2

1

(2.5%)

0

(0%)

1

(5.3%)

Lymphatic invasion

Absent

29

(72.5%)

17

(81%)

12

(63.2%)

0.21§

Present

11

(27.5%)

4

(19%)

7

(36.8%)

Venous invasion

Absent

24

(60%)

13

(61.9%)

11

(57.9%)

0.79§

Present

16

(40%)

8

(38.1%)

8

(42.1%)

pCR

No

34

(85%)

21

(100%)

13

(68.4%)

0.07§

Yes

6

(15%)

0

(0%)

6

(31.6%)

Regression group

3

8

(20%)

7

(33.3%)

1

(5.3%)

<0.01§

2

14

(35%)

13

(61.9%)

1

(5.3%)

1

12

(30%)

1

(4.8%)

11

(57.9%)

0

6

(15%)

0

(0%)

6

(31.6%)

Regression rate

Lo-R

22

(55%)

20

(95.2%)

2

(10.5%)

<0.01 §

Hi-R

18

(45%)

1

(4.8%)

17

(89.5%)

Characteristics

All

(N = 40)

CD8

p-value

Low (N = 18)

High (N = 22)

No.

(%)

No.

(%)

No.

(%)

ypT

ypT0

6

(15%)

0

(0%)

6

(27.3%)

0.02

ypT1

8

(20%)

1

(5.6%)

7

(31.8%)

ypT2

15

(37.5%)

8

(44.4%)

7

(31.8%)

ypT3

11

(27.5%)

9

(50%)

2

(9.1%)

ypN

ypN0

21

(52.5%)

8

(44.4%)

13

(59.1%)

0.36

ypN1

18

(45%)

10

(55.6%)

8

(36.4%)

ypN2

1

(2.5%)

0

(0%)

1

(4.5%)

Lymphatic invasion

Absent

29

(72.5%)

14

(77.8%)

15

(68.2%)

0.72

Present

11

(27.5%)

4

(22.2%)

7

(31.8%)

Venous invasion

Absent

24

(60%)

10

(55.6%)

14

(63.6%)

0.60

Present

16

(40%)

8

(44.4%)

8

(36.4%)

pCR

No

34

(85%)

18

(100%)

16

(72.7%)

0.02

Yes

6

(15%)

0

(0%)

6

(27.3%)

Regression group

3

8

(20%)

6

(33.3%)

2

(9.1%)

<0.01

2

14

(35%)

12

(66.7%)

2

(9.1%)

1

12

(30%)

0

(0%)

12

(54.5%)

0

6

(15%)

0

(0%)

6

(27.3%)

Regression rate

Lo-R

22

(55%)

18

(100%)

4

(18.2%)

<0.01

Hi-R

18

(45%)

0

(0%)

18

(81.8%)