Anticonvulsants that Induce Hepatic Enzymes

Generic Name

Trade Name

Manufacturer

Reference

Phenytoin

Dilantin

Pfizer

[211]

Carbamazapine

Tegretol

Novartis

[212]

Phenobarbital

Phenobarbital

Various

[213]

Primidone

Mysoline

Various

[213]

Oxcarbazapine

Trileptal

Novartis

[214]

Anticonvulsants that Cause Modest or No Hepatic Induction

Generic Name

Trade Name

Manufacturer

Reference

Valproic acid

Depakote

Abb Vie

[215]

Gabapentin

Neurontin

Pfizer

[215]

Felbamate

Felbatol

Mylan

[215]

Lamotrigine

Lamictal

Glaxo Smith Kline

[215] [216]

Topiramate

Topamax

Janssen Pharmaceuticals

[215]

Tiagabine

Gabtril

Teva Pharmaceuticals

[215]

Levetiracetam

Keppra

UCB (Union chimiquebelge)

[216]

Zonisamide

Zonagram

Concordia Pharmaceuticals

[217]

Pregabalin

Lyrica

Pfizer

[218]

Lacosamide

Vimpat

UCB (Union chimiquebelge)

[219]