| Cranial | Toxicity | Improved |
| II pc | 3 (3.6%) | 0 |
| III pc | 0 | 0 |
| IV pc | 0 | 0 |
| V1 pc | 4 (4.9%) | 0 |
| V2 pc | 5 (6%) | 2 |
| V3 pc | 2 (2.4%) | 0 |
| VI pc | 2 (2.4%) | 0 |
| Hypofisis | 3 (3.6%) | 2 |