group

dose

GGT(U/L)

LDH(U/L)

NAG(U/L)

AP/BL

AP+BL

AP/BL

AP+BL

AP/BL

AP+BL

blank control

-

0.62 ± 0.46

0.60 ± 0.24

0.00 ± 0.00

−4.39 ± 0.75

0.84 ± 0.09

9.97 ± 0.93

medium control

-

1.55 ± 0.29^#

1.11 ± 0.10^#

4.47 ± 0.47^##

9.56 ± 1.00^###

1.02 ± 0.06

10.45 ± 0.27

DMSO control

-

1.70 ± 0.89

1.09 ± 0.13^#

6.12 ± 3.95

13.62 ± 3.41^##

1.09 ± 0.09

11.00 ± 1.26

TTE

10 μg・ml⁻¹

3.91 ± 0.50

0.65 ± 0.14

22.71 ± 25.62

7.67 ± 2.45

1.07 ± 0.07

10.61 ± 1.18

40 μg・ml⁻¹

3.60 ± 2.10

1.11 ± 0.18

9.66 ± 3.47

9.38 ± 3.05

1.13 ± 0.05

11.01 ± 1.62

160 μg・ml⁻¹

5.65 ± 3.98

1.90 ± 0.10*

18.70 ± 4.25*

27.33 ± 5.99*

1.19 ± 0.09

10.82 ± 1.33

640 μg・ml⁻¹

3.76 ± 0.22

2.89 ± 0.38**

4.95 ± 0.80

62.20 ± 3.43***

1.24 ± 0.21

11.05 ± 1.12

blank control

-

0.61 ± 0.62

0.16 ± 0.10

0.00 ± 0.00

−0.70 ± 0.78

1.02 ± 0.02

10.13 ± 0.32

medium control

-

1.84 ± 0.25

1.16 ± 0.19^##

3.00 ± 0.48^##

24.63 ± 3.01^##

1.03 ± 0.05

12.31 ± 1.17

DMSO control

-

1.94 ± 0.55

1.22 ± 0.12^###

4.16 ± 1.63^#

31.23 ± 7.33^#

0.95 ± 0.08

12.81 ± 1.90

triptolide

4 ng・ml⁻¹

1.80 ± 0.29

1.11 ± 0.15

1.92 ± 0.44

33.07 ± 5.94

0.93 ± 0.11

12.87 ± 1.70

16 ng・ml⁻¹

1.66 ± 0.86

1.20 ± 0.15

2.24 ± 0.37

36.66 ± 1.23

0.96 ± 0.11

12.96 ± 2.01

64 ng・ml⁻¹

1.40 ± 0.31

1.30 ± 0.12

3.17 ± 0.34

44.30 ± 6.90

1.12 ± 0.11

13.26 ± 1.87

256 ng・ml⁻¹

4.22 ± 0.62**

2.48 ± 0.35*

8.67 ± 1.53*

126.58 ± 14.71**

1.50 ± 0.07*

17.14 ± 0.42*