Organic Syntheses procedure

One-pot procedure

Procedure 1 (NaClO)

Procedure 2 (H₂O₂)

Procedure 3 (O₂)

Penalty [46]

(P)

EcoScale

value (P)

SIS

Penalty [46]

(P)

EcoScale

value (P)

SIS

Penalty [46]

(P)

EcoScale

value (P)

SIS

Penalty [46]

(P)

EcoScale

value (P)

SIS

Step 1

27

73

0.60^*

16

84

0.46^*

16

84

0.51^*

16

84

0.52^*

Step 2

13

87

13

87

13

87

13

87

Step 3

29

71

0.71^**

10

90

15

85

16

84

Step 4

49

51

0.51^**

7

93

7

93

7

93

Summary

118

282

0.22^*

46

354

0.54^*

51

349

0.49^*

52

348

0.48^*