<30%

>30%

p value

Median PFS

7

16

0.004

Median OS

21

26

0.83

<50%

>50%

p value

Median PFS

8

18

0.001

Median OS

21

36

0.009

<90%

>90%

p value

Mean PFS

16.10

37.22

0.014

Mean OS

26.44

51.33

0.017