Variables

Control

a

T2DM

b

T2DM/AS

c

p value

a & b

p value

a & c

p value

b & c

Allele n (%)

n = 162

n = 186

n = 62

ε2

70 (86.4)

82 (91.1)

28 (90.3)

0.23

0.42

0.42

ε3

76 (84.0)

87 (84.4)

29 (83.9)

0.55

0.60

0.60

ε4

16 (19.8)

17 (18.9)

5 (16.1)

0.52

0.44

0.44

Genotype n (%)

n = 81

n = 90

n = 31

ε2/ε3

57 (70.4)

68 (75.6)

23 (74.2)

0.28

0.44

0.44

ε2/ε4

13 (16.0)

14 (15.6)

5 (16.1)

0.55

0.60

0.60

ε2/ε2

/

/

/

/

/

/

ε3/ε3

8 (9.9)

5 (5.6)

3 (9.7)

0.22

0.64

0.64

ε3/ε4

3 (3.7)

3 (3.3)

/

0.61

0.37

0.37

ε4/ε4

/

/

/

/

/

/

HWE

rs7412 (ε2)

39.63 (p < 0.0001)

55 (p < 0.0001)

16.35 (p = 0.00005)

/

/

/

rs429358 (ε4)

0.27 (p = 0.60)

0.43 (p = 0.51)

/

/

/

/