Author’s name

Study type/Country/Year

Reason for exclusion

Kozlowska, A [26]

Prospetive/Poland/2018

This study focused on multivitamins, including folate. It did not focus in any section on folate as an independent factor that can impact gestational diabetes risk

Li, S [18]

Cross-sectional/China/2019

This study did not measure folate intake. Instead, it used serum folate level to relate to the risk of developing gestational diabetes

Barzilay, E [28]

Cohort/Canada/2018

This study measured serum concentrations of one-carbon nutrients, not folate intake

Lai, JS [16]

Cohort/Singapore/2018

This study tried to link serum concentrations of folate along with other vitamins to the risk of gestational diabetes

Araujo, JR

Case-control/Portugal/2012

This study measured folate uptake by primary cultured cytotrophoblasts isolated from human placentas of patients with gestational diabetes and compared them to controls

Reece, EA

Review/USA/2012

This review did not relate folic acid supplementation to the development of gestational diabetes, but it discussed the protective impact of folate on the risk of neural tube defects