Platform

Type of candidate vaccine

Developer

Coronavirus target

Current stage of clinical evaluation/regulatory status Coronavirus candidate

Same platform for non-Coronavirus candidates

Inactivated

Inactivated + alum

Sinovac

SARS-CoV-2

Phase 3

NCT04456595

Phase 1/2

NCT04383574 NCT04352608

SARS

Non-Replicating Viral Vector

ChAdOx1-S

University of Oxford/AstraZeneca

SARS-CoV-2

Phase 3

ISRCTN89951424 Phase2b/3

2020-001228-32

Phase 1/2 PACTR202006922165132 2020-001072-15

MERS, influenza, TB, Chikungunya, Zika, MenB, plague

Non-Replicating Viral Vector

Adenovirus Type 5 Vector

CanSino Biological Inc./Beijing Institute of Biotechnology

SARS-CoV-2

Phase 2 ChiCTR2000031781 Phase 1 ChiCTR2000030906

Ebola

Protein Subunit

Adjuvanted recombinant protein (RBDDimer)

Anhui Zhifei Longcom Biopharmaceutical/Institute of Microbiology, Chinese Academy of Sciences

SARS-CoV-2

Phase 2 NCT04466085 Phase 1 NCT04445194

MERS

RNA

LNP encapsulated mRNA

Moderna/NIAID

SARS-CoV-2

Phase 3 (not yet recruiting) NCT04470427 Phase 2 NCT04405076 Phase 1 NCT04283461

multiple candidates

DNA

DNA plasmid vaccine with electroporation

Inovio Pharmaceuticals/ International Vaccine Institute

SARS-CoV-2

Phase 1/2 NCT04447781 NCT04336410

multiple candidates

DNA

DNA plasmid vaccine + Adjuvant

Osaka University/AnGes/ Takara Bio

SARS-CoV-2

Phase 1/2 NCT04463472

DNA

DNA Vaccine (GX-19)

Genexine Consortium

SARS-CoV-2

Phase 1/2 NCT04445389

DNA

DNA plasmid vaccine

Cadila Healthcare Limited

SARS-CoV-2

Phase 1/2 CTRI/2020/07/026352 (not yet recruiting)

Inactivated

Inactivated

Wuhan Institute of Biological Products/Sinopharm

SARS-CoV-2

Phase 1/2 ChiCTR2000031809

Inactivated

Inactivated

Beijing Institute of Biological Products/Sinopharm

SARS-CoV-2

Phase 1/2 ChiCTR2000032459

Inactivated

Whole-Virion Inactivated

Bharat Biotech

SARS-CoV-2

Phase 1/2 CTRI/2020/07/026300

Protein Subunit

Full length recombinant SARS-CoV-2 glycoprotein nanoparticle vaccine adjuvanted with Matrix M

Novavax

SARS-CoV2

Phase 1/2 NCT04368988

RSV; CCHF, HPV, VZV, EBOV

Protein Subunit

RBD-based

Kentucky Bioprocessing, Inc

SARS-CoV2

Phase 1/2 NCT04473690

RNA

3 LNP-mRNAs

BioNTech/Fosun Pharma/Pfizer

SARS-CoV2

Phase 1/2

2020-001038-36 NCT04368728

Inactivated

Inactivated

Institute of Medical Biology, Chinese Academy of Medical Sciences

SARS-CoV2

Phase 1

NCT04412538