Treatment

Dose (mg/kg)

Number of holes crossed

0 min.

30 mins.

60 mins.

90 mins.

120 mins.

Control

0.1 ml/mous

20.00 ± 1.30

21.20 ± 1.06

21.80 ± 0.97

20.00 ± 1.30

18.60 ± 0.67

Diazepam

1

13.40 ± 1.56

11.40 ± 1.20***

8.00 ± 1.04***

6.20 ± 0.66***

2.40 ± 0.92***

METE

200

19.40 ± 1.96

16.80 ± 0.97*

13.40 ± 0.67***

11.60 ± 0.67***

5.80 ± 0.97***

METE

400

15.20 ± 1.49

15.60 ± 0.98**

11.00 ± 0.83***

9.20 ± 0.58***

3.40 ± 0.92***