Treatment

Urine volume (ml)

1 hr

2 hr

3 hr

4 hr

5 hr

24 hr

2nd day

3rd day

4th day

5th day

10% DMSO

0.56 ± 0.15

1.41 ± 0.27

2.20 ± 0.37

2.85 ±0.41

3.45 ± 0.37

6.40 ± 0.94

9.08 ± 1.33

11.68 ± 1.24

16.30 ± 1.63

22.31 ± 1.55

Furosemide

20 mg/kg

4.25 ± 0.28**

5.96 ± 0.16**

6.28 ± 0.24**

7.61 ± 0.23**

8.25 ± 0.12**

15.51 ± 0.48**

26.18 ± 2.94**

29.93 ± 3.28**

32.71 ± 3.16**

37.56 ± 3.36**

C. jwarancusa 150 mg/kg

0.62 ± 0.14

1.40 ± 0.20

2.33 ± 0.16

2.95 ± 0.26

3.40 ± 0.26

6.41 ± 0.46

11.73 ± 0.84

16.08 ± 1.33

21.08 ± 0.88

27.23 ± 0.94

C. jwarancusa 300 mg/kg

0.95 ± 0.15

1.88 ± 0.35

2.85 ± 0.47

3.6 ± 0.51

4.23 ± 0.49

8.75 ± 0.77

14.55 ± 1.57

20.75 ± 2.08*

26.66 ± 1.72*

30.33 ± 1.94

C. jwarancusa 500 mg/kg

1.36 ± 0.2*

2.71 ± 0.37*

3.66 ± 0.20*

5.13 ± 0.75*

5.75 ± 0.72*

9.51 ± 1.31*

17.91 ± 1.99*

26.16 ± 2.95*

30.25 ± 3.09*

34.0 ± 3.14*