(b) M3G

Parameter

Vehicle

Diclofenac

Tmax (min)

30.0 ± 15.5

90.0 ± 15.4

Cmax (μg/ml)

0.74 ± 0.0091

1.35 ± 0.00322*

AUC (mg/ml∙min)

0.098 ± 0.00923

0.232 ± 0.00442*

t1/2 (min)

21.7 ± 0.211

20.3 ± 0.213