LORIS

LORD

COMET

LORRETA

Phase

III

III

III

III

Study

AS

AS

AS + ET

AS + ET

Screening

MMG

MMG

MMG

MMG, US, MRI

Nuclear Grade

1 or 2

1

1 or 2

1 or 2

Comedo Necrosis

No

No

Eligible

No

ER

N/S

N/S

Positive

Positive

HER2

N/S

N/S

Negative

Negative

Size

N/S

Any Size

Any Size

Equal or less 2.5 cm

Patient/Target

113/932

25/1240

182/1200

27/340