Drugs	Molecule Function	Effect on Disease or Function	Disease or Function	Causal or Correlated	Findings
Atabecestat	BACE Inhibitor	decreases	AD	Causal	1
Bapineuzumab	IgG₁ that binds soluble/fibrillar Aβ	decreases	AD	Causal	7
BAN2401	IgG₁ that binds Aβ protofibrils	decreases	Early Stage AD	Causal	1
Crenezumab	IgG₄ that binds Aβ peptides, oligomers, fibrils and has low affinity for monomers	decreases	AD, Mild AD, Prodromal AD	Causal	4
Elenbecestat	BACE inhibitor	decreases	Mild AD	Causal	1
Gantenerumab	IgG₁ that binds Aβ fibrils	decreases	AD, Early Stage AD, Familial AD, Mild AD, Prodromal AD	Causal	6
Lanabecestat	BACE₁ inhibitor	decreases	AD	Causal	3
Latrepiridine	Antihistamine that modulates neurotransmitters and block Aβ-mediated toxicity	decreases	AD	Causal	7
Semagacestat	γ-secretase inhibitor	decreases	AD	Causal	3
SK-PC-B70M	Protects against Aβ-mediated toxicity	decreases	AD	Causal	1
Solanezumab	IgG₁ that binds Aβ peptides and monomers	decreases	AD, Familial AD, Prodromal AD	Causal	7
Tarenflurbil	NSAID R-enantiomer that modulates γ-secretase activity to reduce Aβ aggregate formation	decreases	AD	Causal	2
Tramiprosate	Taurine derivative that prevents Aβ β-sheet formation	decreases	AD	Causal	3