| DOMESTIC CARNIVORES | |||||||
| Dogs | Ehrlichiosis (Ehrlichia canis) | E | 5 or 10 mg/kg PO BID for 21 days | Comparative efficacy of ENR (2 regimens) and DOX | 13 | Inefficacy of ENR to clear Ehrlichia canis infection | [128] |
| Dogs | Recurrent superficial (S) and deep (D) pyoderma | N | 5 mg/kg PO SID continued up to 1 (S) or 2 (D) weeks after clinical recovery | Efficacy of ENR | 9 (S) + 3 (D) | Efficacy, safety and convenience of ENR | [129] |
| Dogs | Uncomplicated urinary tract infections | N | 18 - 20 mg/kg PO SID for 3 days | Comparative efficacy of ENR (high dose short duration treatment) and AMO-CLA | 68 (35 ENR + 33 AMO-CLA) | Non-inferiority of a high dose short duration ENR treatment | [82] |
| Dogs | Brucellosis (Brucella canis) | N | 5 mg/kg PO BID for 30 days | Efficacy of ENR for the eradication of Brucella canis in a kennel | 12 | Incomplete efficacy of ENR but safety use during gestation | [130] |
| Cats | Chronic bartonellosis (B. henselae and B. clarridgeiae) | N (25 cats) + E (18 cats) | 22.7 mg PO BID for 14 or 28 days | Comparative efficacy of ENR and DOX (each one with 2 treatment durations) | 43 (23 ENR + 17 DOX + 3 controls) | Efficacy of high dose long duration ENR treatment (4 to 6 weeks) | [131] |
| Cats | Conjunctivitis (Chlamydophila felis) | N | 5 mg/kg SC SID for 3 days then PO SID for 11 days | Comparative efficacy of ENR and DOX | 25 (14 ENR + 11 DOX) | Equal improvement of ENR and DOX in clinical signs and infection status | [132] |
| RODENTS | |||||||
| Mice | Systemic infections (Escherichia coli) | E | 5 mg/kg SC or PO | Efficacy of ENR (2 different routes of administration) | NP | Efficacy of ENR and superiority of the injectable form (SC) | [133] |
| Calomys callosus | Toxoplasmosis (Toxoplasma gondii) | E | 3 mg/kg SC SID for 3 days | Comparative efficacy of ENR and SUL | 15 (5 ENR + 5 SUL + 5 controls) | Efficacy of ENR as a potential alternative drug | [134] |
| LAGOMORPHS | |||||||
| Rabbits | Pasteurella multocida (Pam) | N (11 rabbits) + E (12 rabbits) | 5 mg/kg SC BID for 10 days | Efficacy of ENR in the elimination of Pam from asymptomatically infected rabbits | 11 (N) + 12 (E) | Inefficacy of ENR to eliminate Pasteurella multocida | [135] |
| CRUSTACEANS | |||||||
| Artemia franciscana (nauplii) | Vibrio harveyi (strain PN9801) | E | ENR 4h before infection (A) or 24 h after infection (B) | Comparative efficacy of ENR (2 regimens) | 600 | Efficacy of ENR to stop the course of a bacterial infection in Artemia franciscana | [136] |