Atorvastatin Calcium Solubility study

Media

Solubility (mg/mL)

Volume of solvent in mL/1 g (mL)

USP Solubility scale

0.1N HCl

0.0254

39370.1

Practically insoluble

0.01N HCl

0.0315

31746.0

Practically insoluble

pH 4.5

0.0570

17543.9

Practically insoluble

pH 5.5

0.1701

5878.9

Very slightly soluble

pH 6.8

0.2838

3523.6

Very slightly soluble