Finding or quantity

pEDS femalesa

+/total (%)

pEDS malesb

+/total (%)

EDS femalesc

# (%)

EDS malesd

# (%)

Patient

reporte

Number of patients

27

16

596 (100)

114 (100)

1

Percentage female

27 (63)

--

596 (84)*

--

1 (100)

Periodontitis

25/26 (96)*

11/11 (100)*

83 (14)

13 (11)

-**

Many caries (poor enamel)

--

--

268 (45)#

29 (25)

+

Gingival recessions

24/25 (96)

10/10 (100)

--

--

-**

Gum bleeding

23/24 (92)

3/5 (60)

--

--

-**

Gum fragility

14/15 (93)

5/5 (100)

--

--

-**

Later bone resorption

--

--

+

Dental crowding

--

--

375 (63)

57 (50)

+

Marfanoid (aged) facies

--

--

9 (1.5)

1 (1.0)

-

TMJ issues

--

--

334 (56)#

36 (32)

+

Hypermobility

17/21 (81)#

3/9 (33)

536 (90)#

89 (78)*

+

Joint dislocation

2/21 (9.5)

2/27 (7.4)

429 (72)*#

59 (52)*

-

Arthralgia

8/22 (36)

9/28 (32)

530 (89)*#

72 (63)*

-

Scoliosis

4/21 (19)

4/26 (15)

238 (40)*#

33 (29)

+

Flat feet

--

--

185 (31)

34 (30)

+

Easy bruising

23/24 (96)*

31/32 (97)*

387 (65)#

51 (45)

+

Fragile skin

21/25 (84)

7/10 (70)

548 (92)#

76 (67)

+

Elastic skin

17/22 (77)*

21/28 (75)*

149 (25)#

18 (16)

+

Abnormal scars

10/22 (46)

13/30 (43)*

256 (43)#

26 (23)

-**

Prominent vasculature

7/16 (44)

2/4 (50)

185 (31)

27 (24)

+

Pretibial discoloration

19/25 (76)

27/35 (77)

--

--

?

IBS symptoms

--

--

542 (91)#

68 (60)

+

POTS symptoms

--

--

578 (97)#

81 (71)

+

MCAD symptoms

-

--

524 (88)#

67 (59)

+

Hernia

4/20 (20)

1/5 (20)

72 (12)#

3 (3.0)

-**

Prone to infections

5/20 (25)

2/4 (50)

--

--

-**

Aneurysms (5, 6, 14)

2/19 (11)*

1/6 (16)*

4 (0.67)

0 (0.0)

-**

Organ rupture (1-III-10)

0/15 (0)

1/4 (25)*

2 (0.34)

0 (0.0)

-