Variable

Controls

Non-users

Intervention

p-value

(n = 75)

(n = 70)

(n = 108)

Age (years)

56 (47 - 64)

52 (39 - 62)

53 (42 - 64)

p = 0.4

Male sex (%)

56

59

56

p = 0.9

Actual bodyweight (kg)

85 (66 - 97)

88 (64 - 107)

78 (67 - 96)

p = 0.7

<60 kg

13%

20%

10%

p = 0.2

60 - 80 kg

25%

20%

46%

p < 0.005

81 - 100 kg

40%

29%

21%

p = 0.02

>100 kg

21%

31%

22%

p = 0.3

eGFR (ml/min/1.73 m²)

89 (56 - 109)

81 (54 - 114)

70 (47 - 102)

p = 0.2

<15 or RRT

12%

24%

15%

p = 0.1

15 - 49

19%

11%

19%

p = 0.4

50 - 90

32%

24%

39%

p = 0.1

>90

37%

40%

28%

p = 0.2

Vancomycin TDD (mg)

2000 (2000 - 2250)

2000 (1250 - 3000)

2000 (1250 - 2500)

p = 0.5