Characteristics

Hyperfiltration present

n (%)

n = 51 (33.3)

Hyperfiltration absent

n (%)

n = 102 (66.7)

P-value

Age group

10 - 13 years

14 - 16 years

17 - <19 years

29 (56.9)

18 (35.3)

4 (7.8)

41 (40.2)

39 (38.2)

22 (21.6)

0.05

Gender

Female

Male

28 (54.9)

23 (45.1)

51 (50)

51 (50)

0.609

Haemoglobin Variants

Hb SS

HB SC

Sickle B⁺ thal

Other

47 (92.2)

4 (7.8)

0 (0.0)

0 (0.0)

68 (66.7)

27 (26.5)

5 (4.9)

2 (2.0)

0.007

History of Acute events

Severe recurrent VOC

Acute chest syndrome

Cerebrovascular accident

Acute sequestration crisis

Combination of ACS/CVA

None

21 (41.2)

9 (17.6)

5 (9.8)

1 (2.0)

1 (2.0)

14 (27.5)

28 (27.5)

19 (18.6)

7 (6.9)

2 (2.0)

1 (1.0)

45 (44.1)

0.405

History of Chronic Blood Transfusion

Yes

No

5 (9.8)

46 (90.2)

17 (16.7)

85 (83.3)

0.331

History of Hydroxyurea therapy

Yes

No

31 (60.8)

20 (39.2)

39 (38.2)

63 (61.8)

0.01