Authors, place and year of study, sample size | Frequency of bone fragility (osteopenia and/or osteoporosis) | Factors associated with bone fragility |
Gabriel bandzanni and al, Brésil, 2011, n = 65 | 81.5% (57 % ostéopénia and 24.5% ostéoporosis) | Low GFR, severe anaemia with p = 0.02, low BMI with p = 0.17 |
Mona Sarrai and al, 2007, NY, USA, n = 103 | 79.6% | Homozygous phenotype with p = 0.018; Severe anaemia with p < 0.0001, High ferritinaemia with p = 0.010, Low BMI with p = 0.003 |
Redonda G Miller and al, JH, 2006, USA, n = 32 | 72% | BMI with p = 0.007, sex M with p = 0.02, homozygous phenotype SS |