Category

Feature

Value

References

Epidemiology

Primary cardiac lymphoma

1% - 2% of all cardiac tumors

[1] [2] [17]

Secondary cardiac involvement

Up to 20% of NHL cases

Age at diagnosis

Median

55 - 65 years

[3] [4] [5]

Range

10 - 83 years

Sex

Male

65% - 85%

[3] [4]

Female

15% - 35%

Presenting features

Heart failure

31% - 78%

[3] [4] [9] [10] [32]

Chest pain

19% - 46%

Arrhythmia

8% - 56%

Constitutional symptoms

7% - 26%

SVC syndrome

5% - 15%

Location and involvement

Right atrium

66% - 77%

[4] [32]

Right ventricle

25% - 37%

Left atrium

12% - 30%

Left ventricle

2% - 21%

Septum

2% - 41%

Pericardial effusion

30% - 58%

Histology

DLBCL

71% - 92%

[3] [4] [32]

Burkitt

7% - 8%

CLL/SLL

4% - 8%

T cell

3% - 5%

Other or NOS

Up to 10%

Treatment

Chemotherapy

52% - 89%

[3] [4] [32]

Surgery

16% - 28%

Radiation

8% - 20%

Combination therapy

12% - 23%

Outcomes

Median OS

3 - 63 months

[3] [4]