Case 1

Case 2

Case 3

Age (years)

73

55

80

Sex

Male

Female

Female

Presentation

Dyspnea

Peripheral edema

Dyspnea

Substernal chest pain

Dyspnea

Weakness

ECG

Right bundle branch block

Prolonged QTc

First-degree AV block

Prolonged QTc

Atrial fibrillation

Prolonged QTc

Echocardiogram

12.1 cm mass in the RV

3.1 cm mass in the RA

4.0 cm mass in the RA

Other Imaging

Cardiac MRI

CT C/A/P

Cardiac MRI

CT C/A/P

PET/CT

CT Chest

HIV Status

Negative

Negative

Not assessed

EBV Serology

Not assessed

Positive IgG

Not assessed

Tissue Sampling

Biopsy

Biopsy

Autopsy

Diagnosis

DLBCL

DLBCL

DLBCL

Treatment

R-COEP × 2

R-CVP × 1

R-CHOP × 2

None

Survival

2 months

Lost to follow-up

1 week