Sample type

Serum

Exosome-enriched serum

FFPE tissue

DLBCL patients

Number

(Female; male)

33

(13; 20)

28

(12; 16)

22

(9; 13)

Age, median

(range)

67

(36 - 84)

68.5

(38 - 84)

67.5

(46 - 83)

Stage

I

3

2

2

II

7

7

3

III

6

4

5

IV

17

15

12

B symptom

10

9

9

Performance status at diagnosis

0, 1, 2

30

25

20

3, 4

3

3

2

Serum lactate dehydrogenase (LDH) level, IU/L

Median

(range)

237

(138 - 8472)

242

(138 - 8472)

276.5

(161 - 8472)

Elevated (>240)

16

14

12

Extra nodal disease, number

0

12

10

8

1

12

11

10

2

8

6

4

3

1

1

0

International Prognostic Index (IPI)

Low

6

4

2

Low-intermediate

15

12

12

High-intermediate

8

8

6

High

4

4

2

Immunohistochemical grouping (Hans’ algorithm)

GCB

14

13

8

Non-GCB

16

13

12

Not applicable

3

2

2

Healthy volunteers (control)

Number

(Female; male)

22

(9; 13)

19

(9; 10)

6^*

(5; 1)

Age, median

(range)

62

(20 - 76)

62

(39 - 76)

51.5

(40 - 69)