Authors

Random

Allocation

Double-blind

FSD

FSFI

Drop out (%)

Adverse effects

Ito et al. 2006 [7]

+

HSDD

FSFI modified

0

No significant difference in adverse effects

Chedraui et al. 2006 [8]

+

+

KI

11.7

Not described

Akhtari et al. 2014 [9]

+

+

+

HSDD

+

10.4

Only one patient reported grade 1 abdominal cramp.

Rao et al. 2015 [10]

+

+

+

HSSD

+

0

No significant difference in adverse effects

Zeinalzadeh et al. 2016 [11]

+

+

+

HSSD

+

10.7

Not described

Postigo et al. 2016 [13]

+

FSD

SQ-F, FIEI

0

No significant difference in adverse effects

De Souza et al. 2016 [12]

+

+

HSDD

+

20

Not described

Vale et al. 2017 [14]

+

HSDD

+

37.5

Not described

Bernorio et al. 2018 [15]

+

+

+

FSD

+

3.3

Both products were very well tolerated

Caruso et al. 2018 [20]

+

HSDD

+

26.9

Not described

Caputo et al. 2018 [21]

FSD

+

3.3

Not described

DRUG-INDUCED FSD (DIFSD)

Meston et al. 2008 [16]

+

FSD + DIFSD

+

19.1

Not described

Kashani et al. 2012 [17]

+

DIFSD

+

10.5

Described with no differences

Farnia et al. 2015 [18]

+

+

DIFSD

+

0

No side effects

Farnia et al. 2017 [19]

+

+

DIFSD

+

0

Not described