| Characteristics | Hazard ratio (95% CI) | p | Adjusted Hazard ratio (95% CI) | p |
| Age (years) |
|
|
|
|
| 22 - 35 | 1 | - |
|
|
| 36 - 40 | 1.43 (0.46 - 4.52) | 0.538 |
|
|
| 41 - 48 | 0.57 (0.14 - 2.40) | 0.446 |
|
|
| 49 - 69 | 0.69 (0.18 - 2.56) | 0.578 |
|
|
| Sex |
|
| ||
| Male | 1.81 (0.21 - 1.46) | 0.230 |
|
|
| female | 1 | - |
|
|
| Tobacco |
|
|
|
|
| Yes | 0.78 (0.10 - 5.82) | 0.806 |
|
|
| No | 1 | - |
|
|
| Alcohol |
|
|
|
|
| Yes | 1.06 (0.40 - 2.79) | 0.907 |
|
|
| No | 1 | - |
|
|
| ART adherence |
|
|
|
|
| Yes | 1 | - | - | - |
| No | 4.69 (1.66 - 13.26) | 0.0035 | 1.41 (1.20 - 2.66) | 0.021 |
| BMI |
|
|
|
|
| <18.5 | 1 | - |
|
|
| ≥18.5 | 0.74 (0.30 - 1.85) | 0.525 |
|
|
| Anemia |
|
|
|
|
| Yes | 4.05 (1.18 - 13.93) | 0.026 | 1.64 (1.07 - 15.81) | 0.039 |
| No | 1 | - |
|
|
| CD4 cells count (µL) |
|
|
|
|
| <50 | 1 | - |
|
|
| 51 - 200 | 0.12 (0.03 - 0.49) | 0.003 | 0.08 (0.02 - 0.34) | < 0.001 |
| 201 - 350 | 0.14 (0.04 - 0.49) | 0.002 | 0.23 (0.06 - 0.84) | 0.027 |
| >350 | 0.15 (0.05 - 0.48) | 0.001 | 0.21 (0.06 - 0.82) | 0.024 |
| WHO clinical staging |
|
|
|
|
| Stage I | 1 | - |
|
|
| Stage II | 0.00 (0.00 - 1.01) | 0.989 | 0.01 (0.00 - 1.91) | 0.698 |
| Stage III | 0.87 (0.24 - 3.12) | 0.830 | 0.58 (0.14 - 2.39) | 0.454 |
| Stage IV | 5.12 (1.22 - 21.48) | 0.025 | 4.01 (1.90 - 18.81) | 0.047 |
| Opportunistic infections |
|
|
|
|
| Yes | 2.71 (1.07 - 6.89) | 0.036 | 2.02 (0.68 - 6.03) | 0.210 |
| No | 1 | - |
|
|
| Co-infection TB/HIV |
|
|
|
|
| Yes | 1.55 (0.59 - 4.09) | 0.373 |
|
|
| No | 1 | - |
|
|