Neuraxial anesthesia (N = 439,583)

General anesthesia (N = 26,431)

Crude OR (95% CI)

P-value^a

Adjusted OR^b (95% CI)

P-value^a

Death or cardiac arrest (missing = 2)

27 (0.6 per 10,000)

--^c

--^c

0.096

2.44 (0.67 - 8.93)

0.18

Anesthesia-related complications

2540 (57.8 per 10,000)

217 (82.1 per 10,000)

1.42 (1.24 - 1.64)

<0.001

1.62 (1.37 - 1.92)

<0.001

Severe anesthesia-related complications^d (missing = 2)

118 (2.7 per 10,000)

18 (6.8 per 10,000)

2.54 (1.55 - 4.17)

<0.001

2.86 (1.58 - 5.19)

<0.001

Surgical site infections

2812 (64.0 per 10,000)

342 (129.4 per 10,000)

2.04 (1.82 - 2.28)

<0.001

1.74 (1.47 - 2.06)

<0.001

Venous thromboembolic events

311 (7.1 per 10,000)

31 (11.7 per 10,000)

1.66 (1.15 - 2.40)

0.009

1.92 (1.23 - 2.97)

0.004