Recorded clinical indication for general anesthesia (N = 398,044)

No recorded clinical indication for general anesthesia (N = 466,014)

P-value^a

Exposure

General anesthesia

34,071 (8.56%)

26,431 (5.67%)

<0.001

Adverse events

Death or cardiac arrest (missing = 4)

261 (6.6 per 10,000)

31 (0.7 per 10,000)

<0.001

Anesthesia-related complications

2345 (58.9 per 10,000)

2757 (59.2 per 10,000)

0.89

Severe anesthesia-related complications (missing = 4)^b

341 (8.6 per 10,000)

117 (2.5 per 10,000)

<0.001

Surgical site infection

4226 (106.2 per 10,000)

3154 (67.7 per 10,000)

<0.001

Venous thromboembolic events

710 (17.8 per 10,000)

342 (7.3 per 10,000)

<0.001