Group K (n = 20)

Group D (n = 20)

Group C (n = 20)

P-value¹

P-value²

P-value³

P-value⁴

Mean ± SD

Mean ± SD

Mean ± SD

IL-1

Baseline

3.46 ± 3.11

3.61 ± 2.87

3.33 ± 3.02

0.798

0.735

0.797

0.482

Pre-infiltration

3.75 ± 2.65

3.26 ± 2.50

3.28 ± 2.86

0.401

0.304

0.213

0.725

After 6 h

3.61 ± 3.01

3.37 ± 2.44

3.23 ± 2.92

0.655

0.968

0.516

0.351

P-value⁵

0.185

0.490

0.122

After 24 h

3.40 ± 2.55

3.35 ± 2.55

3.35 ± 3.01

0.798

0.808

0.473

0.745

P-value⁶

0.051

0.872

0.432

IL-6

Baseline

1.34 ± 0.20

1.33 ± 0.18

1.36 ± 0.26

0.986

0.892

0.935

0.892

Pre-infiltration

138.58 ± 92.07

134.73 ± 75.35

138.26 ± 74.42

0.987

0.914

0.946

0.882

After 6 h

81.07 ± 52.18

93.97 ± 61.26

119.56 ± 66.29

0.125

0.499

0.028*

0.046*

P-value⁵

0.000*

0.000*

0.000*

After 24 h

75.44 ± 53.86

86.50 ± 55.67

125.88 ± 74.99

0.032*

0.337

0.013*

0.034*

P-value⁶

0.000*

0.000*

0.009*

IL-10

Baseline

1.78 ± 0.89

1.90 ± 0.97

1.78 ± 1.04

0.779

0.675

0.715

0.507

Pre-infiltration

10.24 ± 8.84

11.01 ± 8.94

10.21 ± 8.96

0.863

0.715

0.871

0.598

After 6 h

35.93 ± 14.07

22.17 ± 17.71

8.48 ± 8.33

0.000*

0.001*

0.000*

0.000*

P-value⁵

0.000*

0.001*

0.015*

After 24 h

40.95 ± 10.90

23.86 ± 11.22

8.02 ± 7.04

0.000*

0.000*

0.000*

0.000*

P-value⁶

0.000*

0.001*

0.008*

TNF

Baseline

49.37 ± 38.71

49.25 ± 37.92

47.31 ± 38.27

0.922

0.892

0.705

0.776

Pre-infiltration

111.16 ± 46.16

106.47 ± 48.27

106.15 ± 47.89

0.926

0.725

0.745

0.989

After 6 h

65.05 ± 38.15

77.33 ± 27.59

92.17 ± 21.09

0.018*

0.044*

0.011*

0.032*

P-value⁵

0.002*

0.000*

0.000*

After 24 h

54.31 ± 32.81

69.25 ± 37.88

90.97 ± 32.37

0.003*

0.058

0.002*

0.025*

P-value⁶

0.000*

0.000*

0.000*