Author	Year	Sample Examined	Technology	Comparison Technology	Important Findings
Besnard et al. [6]	2021	Healthy carious and non-carious human dental enamel	Synchrotron X-ray MCT	Optical microscopy, electron microscopy (ion beam scanning), and X-ray conventional tomography	Clear contrast was obtained with Synchrotron X-ray MCT. Improved quantification of lesion depth function through volume fraction of demineralized content, voids cross-sectional area estimation, and aspect ratio achieved through D and 2D image segmentation. Within the same lesion, a transition between type 1 and type 2 lesions was identified.
Bollmann et al. [14]	2022	Transferability from tablets to oral films of X-ray MCT virtual matrice to be used in validation concept	X-ray micro-computed tomography	Confocal Raman microscopy	The obtained images confirmed the transferability of the validation concept. The combination of X-ray MCT and Raman microscopy figured out artifacts in images due to the presence of air bubbles in oral films. Therefore, the final raw images were with artifacts and the film virtual matrix did not be used in silico calculations as no real oral film representation was found.
Esentürk et al. [10]	2020	Root canal morphology	Micro-computed tomography	Rotary and conventional files in the young permanent and primary teeth	The MCT showed that Revo-S rotary file instrumentation significantly improved root canal surface area and volume (p < 0.001). A significant reduction in apical transport was observed in primary molars in comparison to permanent teeth (p < 0.001).
Colombo et al. [14]	2019	archaeological teeth mineral matrix	Micro-computed tomography		Through the IGD mineral matrix, vitamin D deficiency was detected in the archaeological samples under environmental and dietary habits.
Aktuna Belgın et al. [15]	2019	dentin and enamel	Micro-computed tomography	Periapical radiographs	Measurement of enamel and dental thickness accuracy and reliability through analysis of intra and inter-observation.