No.

Age/sex

Site

Smoking history

Histology

Cell size of NEC

IHC of NEC

IHC of SCC

Follow-up

Reference

1

63/M

Retromolar

NA

NEC

Small

NA

-

DOD at 24 mths

Benning, et al. 1990 [11]

2

76/M

Tongue

Yes

NEC

Small

+Keratin, EMA, CEA, NSE

-

DUC at 2 mths

Yoshida, et al. 1995 [12]

3

46/F

Mandible

NA

TC

-

+CGA, NSE

-

NED at 24 mths

Coleman, et al. 1996 [13]

4

49/M

Floor of mouth

Yes

NEC

Medium to large

+CGA, SYP, CT, LMW-CK

-

DOD at 10 days

Baker, et al. 1999 [14]

5

59/M

Gingiva

NA

NEC and SCC

Large

+CGA, CD56

+CAM5.2

NA

Oku, et al, 2002 [8]

6

68/M

Gingiva

NA

AC

-

+CGA,SYP, NSE, CAM5.2, AE1/AE3

-

NA

Abiko, et al. 2004 [15]

7

79/M

Tongue

NA

NEC

Large

+CD56, NSE, p16, p53, p63, 34βE12, CK5/6, CK19

-

NED at 18 mths

Kusafuka, et al. 2009 [16]

8

62/F

Gingiva

NA

NEC and SCC

Small

+CGA, SYP, CD56, NSE, K7, K19

+K5, K14, K15, K17, p63

NED at 23 mths

Mochizuki, et al. 2010 [7]

9

34/F

Retromolar

NA

NEC

Large

+CGA, CD56, CD57, S100P, Keratin, EMA

-

AWD at 9 mths

Krishnamurthy, et al. 2011 [17]

10

46/F

Retromolar

NA

TC

-

+CGA, SYP, NSE, AE1/AE3, CK7, p63, S100, Vimentin, CD57

-

NED at 11 mths

Yang, et al., 2011 [18]

11

57/M

Uvula

NA

AC

-

+SYP, EMA, AE1/AE2

-

DOD at 9 mths

Goldman, et al., 2012 [19]

12

25/F

Gingiva

NA

NEC

Medium to large

+SYP, NSE, S100

-

NED at 13 mths

Wu, et al. 2014 [3]

13

38/F

Buccal mucosa

NA

NEC

Small

+SYP, EMA, AE1/AE3

-

NED at 8 mths

Wu, et al. 2014 [3]

14

73/M

Gingiva

Yes

NEC

Small

+CGA, SYP, NSE, AE1/AE3

-

NED at 14 mths

Zeng, et al. 2015 [4]

15

65/M

Floor of mouth

NA

AC and SCC

-

+SYP, CD56

+34βE12, p63

AWRR at 6 mths

Yamagata, et al. 2016 [6]

16

59/M

Soft palate

Yes

NEC and SCC

Small

+CGA, SYP, CD56, p16

+34βE12, p63, p16

NED at 30 mths

Our case