Effect of oral appliances on vascular disease

Gotsopoulos et al. (2004)

3.5 mmHg drop in the systolic and diastolic blood pressure with oral appliance treatment, but only during wakefulness. There was no change in blood pressure during sleep.

Barnes et al. (2004)

Significant reduction in nighttime diastolic blood pressure by 2.2 mmHg. There were no changes in diastolic blood pressure during wakefulness and no changes in systolic blood pressure either during wakefulness or sleep.

Yoshida (2006)

Significant reduction in blood pressure from 132.0/82.1 to 127.5/79.2 mmHg.