Ref. | Study Type | Intervention | Population/Sample Size | Results/Benefits | Adverse Effects |
[40] | Randomized DB PC Trial | 1.5g calcium/day or placebo | 8325 women < 20 week pregnancy | Did not prevent pre-eclampsia but did reduce its severity and maternal morbidity | Not Reported |
[41] | Randomized DB PC Trial | 2g calcium/day or placebo | 4589 women (13 - 21 weeks pregnancy) | No prevention in pre-eclampsia, or its severity or delay its onset | Not Reported |
[42] | Systematic Review | 1.5g to 2 g calcium/day | 12 RCTs with 15,528 women | Appears to reduce the risk of pre-eclampsia and serious morbidity | No other clear benefit or harms |
[10] | Randomized DB PC Trial | 2g calcium/day or placebo | 30 women (28 to 32 weeks of gestation) | Limited data shows reduction in the risk of pre-eclampsia | Not Reported |