Ref.

Study Type

Intervention

Population/Sample Size

Results/Benefits

Adverse Effects

[40]

Randomized DB PC Trial

1.5g calcium/day or placebo

8325 women < 20 week pregnancy

Did not prevent pre-eclampsia but did reduce its severity and maternal morbidity

Not Reported

[41]

Randomized DB PC Trial

2g calcium/day or placebo

4589 women (13 - 21 weeks pregnancy)

No prevention in pre-eclampsia, or its severity or delay its onset

Not Reported

[42]

Systematic Review

1.5g to 2 g calcium/day

12 RCTs with 15,528 women

Appears to reduce the risk of pre-eclampsia and serious morbidity

No other clear benefit or harms

[10]

Randomized DB PC Trial

2g calcium/day or placebo

30 women (28 to 32 weeks of gestation)

Limited data shows reduction in the risk of pre-eclampsia

Not Reported