${K}_{T}$ | Death rate of wild-type and mutant tumor cells due to chemotherapy | $\left(8.1\times {10}^{-1}\right)\cdot X$ | day | [25] , [32] |

${K}_{AT}$ | Chemotherapy-induced death rate of wild-type and mutant tumors due to mAbs cetuximab and panitumumab | $4\times {10}^{-4}$ | L mg | [32] |

${\delta}_{T}$ | Chemotherapy efficacy coefficient on wild-type and mutant cancer cells | $2\times {10}^{-1}$ | L mg | [32] |

Y | Determines the percent level of the maximum rate of mAb-induced tumor death of wild-type and mutant cells | 0.75 | unitless | [32] |

$\psi $ | Rate of mAb-induced wild-type and mutant tumor cell death | $\left(2.28\times {10}^{-2}\right)\cdot Y$ for cetuximab $\left(3.125\times {10}^{-2}\right)\cdot Y$ for panitumumab | L mg | [32] |

f | Rate of NK cell turnover | $1\times {10}^{-2}$ | day | [32] |

e | Rate of NK synthesis from circulating lymphocytes | $\frac{1}{9}\cdot f$ | day | [32] |

${g}_{N}$ | IL-2 concentration needed for half-maximal NK cell proliferation | $2.5036\times {10}^{5}$ | IU L | [32] |

${p}_{N}$ | Rate of IL-2-induced NK cell proliferation | $5.13\times {10}^{-2}$ | day | [32] |

p | Rate of NK cell death due to interaction with the tumor | $5.156\times {10}^{-14}$ | cell | [32] |

${p}_{A}$ | Rate of NK cell death due to interaction with mAbs complexes | $6.5\times {10}^{-10}$ (0 for panitumumab) | cell | [32] |

${K}_{N}$ | Rate of NK cell depletion due to chemotherapy toxicity | $9.048\times {10}^{-1}$ | day | [32] |

${\delta}_{N}$ | Coefficient of chemotherapy toxicity on NK cells | $2\times {10}^{-1}$ | L mg | [32] |

m | Rate of turnover of activated CD8+ T cells | $5\times {10}^{-3}$ | day | [32] |

$\theta $ | IL-2 concentration required to halve the CD8+ T cell turnover rate | $2.5036\times {10}^{-3}$ | IU L | [32] |

q | Rate of CD8+ T cell death due to interaction with the tumor | $5.156\times {10}^{-17}$ | cell | [32] |

${r}_{1}$ | Rate of activation of CD8+ T cell due to NK cell-lysed tumor cell debris | $5.156\times {10}^{-12}$ | cell | [32] |

${r}_{2}$ | Rate of CD8+ T cell production from circulating lymphocytes | $1\times {10}^{-15}$ | cell | [32] |