Parameter

Description

Value

Units

Ref.

$a_w$

Tumor growth rate

(colorectal cancer)

$2.31\times {10}^{-1}$

day⁻¹

[32]

c

Rate of NK cell-induced tumor death

$5.156\times {10}^{-14}$

L cell⁻¹ day⁻¹

[32]

d

Immune strength coefficient

{1.3, 1.6, 2.1}

day⁻¹

[32]

l

Immune system strength scaling coefficient

{1.1, 1.4, 2}

unitless

[32]

s

Value describing how quickly CD8+ T cells respond to the presence of a tumor

$\left\{5\times {10}^{-3},8\times {10}^{-3},4\times {10}^{-2}\right\}$

L

[32]

$\xi$

Rate of NK cell-induced tumor death through antibody-dependent cellular cytotoxicity (ADCC)

$6.5\times {10}^{-10}$

(0 for panitumumab)

L cell⁻¹ day⁻¹

[32]

$h_1$

Concentration of mAbs necessary for half-maximal increase in ADCC activity

$1.25\times {10}^{-6}$

(0 for panitumumab)

mg L⁻¹

[32]

X

Determines the percent level of the maximum rate of chemotherapy-induced tumor death of wild-type and mutant cells

0.75

unitless

[32]