Variable

DO present

DO absent

P value

Gender

Male

Female

6

16

2

8

1

Age/years

Mean ± SD

Median (range)

33 ± 4

33 (26 - 39)

29.6 ± 5.2

29 (33 - 35)

0.07

Age of onset/years

Mean ± SD

Median (range)

27.4 ± 6

29 (17 - 63)

27 ± 5

27 (20 - 33)

1

Duration of illness/years

Mean ± SD

Median (range)

5 ± 2.8

5 (1 - 9)

2.4 ± 0.5

2 (2 - 3)

0.01

Time between attacks/months

Mean ± SD

Median (range)

15.3 ± 13

12 (1 - 36)

8.4 ± 9.3

4 (1 - 24)

0.15

EDSS

Mean ± SD

Median (range)

5 ± 1

5 (3 - 6)

2.6 ± 1

3 (1 - 4)

0.0001

Number of attacks

Mean ± SD

Median (range)

3.5 ± 1.6

3 (1 - 6)

2.2 ± 0.4

2 (2 - 3)

0.01