Methylation Type

Diseases Associated

Biomarkers

References

DNA Hypermethylation

Different Cancer Types

APC, RASSF1A, CDH13, p16INK4a, MGMT, p73, BRCA1

[33] [39] [40]

DNA Hypomethylation

Different Cancer Types

TERT, Dlk1/Gtl2

[41] [42]

Imprinted Gene Methylation

Imprinted Disorders

H19, Igf2,

[43]

X-Chromosome Inactivation

X-linked Disorders

XIST, MEG3, SNRPN

[44] [45]

LINE-1 Methylation

Cancer, Alzheimer’s Disease

LINE-1 Repeat Elements

[46] [47]

Repeat Element Methylation

Autism disorder

Alu, LINE-1 repeat Element

[48]