A significant decrease of cutaneous microcirculation characterizes a soothing effect of the product.

Before/after

Subject

D0

D28

D56

Δ D28

Δ D56

1

154

147

153

−7

−1

2

165

140

153

−25

−12

3

193

186

183

−7

−10

4

184

175

185

−9

1

5

158

141

147

−17

−11

6

202

167

177

−35

−25

7

158

149

160

−9

2

8

221

198

186

−23

−35

9

200

183

183

−17

−17

10

185

155

165

−30

−20

11

137

140

137

3

0

12

166

149

155

−17

−11

13

155

151

156

−4

1

14

160

161

165

1

5

15

107

114

UN

7

UN

16

205

196

200

−9

−5

17

135

144

135

9

0

18

151

149

142

−2

−9

19

106

109

110

3

4

20

142

NC

138

NC

−4

21

134

(157) * AV

135

(23) * AV

1

22

158

167

MV

9

MV

Mean

162.5

156.1

158.3

−9.0

−7.3

Median

158.0

150.0

155.5

−8.0

−4.5

Minimum

106.0

109.0

110.0

−35.0

−35.0

Maximum

221.0

198.0

200.0

9.0

5.0

SEM

6.5

5.3

5.0

2.9

2.4

CI 95%

13.5

11.1

10.5

6.0

5.0

Nb of subjects

22

20

20

20

20

Statistical analysis p =

0.006

0.006

Statistical test

T. test

T. test

Δ%

−4%

−3%

% of subjects with soothing effect (variation < −0.1)

70%

60%