| Etiological factor | Patients No. | % |
| Candidates are not suitable for the procedure | 12 | 34.28% |
| Non-compliance with the (FDA) indication | 9 | 25.7% |
| Filler injected in a wrong place | 9 | 25.7% |
| Injection of a large quantity than required | 18 | 51.4% |
| Frequent and long-term injection | 5 | 14.2% |
| Non-trained hands | 15 | 42.8% |
| Lack of scientific knowledge | 17 | 48.5% |
| The use of (FDA) unapproved products | 13 | 37.1% |