| Column | Hypersil BDS C18 | Symmetry C18 | Amine Capillary | ||
250 × 4.6 mm 5 µm | 100 × 2.0 mm 2.4 µm | 150 × 4.6 mm 5 µm | 75 × 4.6 mm 3.5 µm | 320 × 0.075 mm | ||
Ketamine | RSDa | 1.73 | 3.34 | 1.58 | 0.19 | 0.36 |
Rsb | 0.56 | 0.88 | 1.26 | 1.30 | 4.97 | |
LOD (pgoncolumn) | 3.9 | 1.02 | 7.70 | 7.60 | 0.0043 | |
K' | 1.27 | 3.55 | 1.11 | 1.28 | 1.40 | |
Α | 1.13 | 1.15 | 1.18 | 1.23 | 1.17 | |
W | 0.52 | 0.65 | 0.16 | 0.12 | 0,12 | |
T | 2.7 | 1.8 | 1.1 | 1.3 | 1.5 | |
N | 1030 | 1063 | 3268 | 2138 | 40,009 | |
Lidocaine | RSDa | 0.26 | 2.97 | 1.48 | 0.14 | 0.36 |
Rsc | 2.21 | 3.42 | 3.41 | 2.71 | 1.53 | |
LOD (pgoncolumn) | 2.00 | 0.70 | 3.90 | 4.10 | 0.0053 | |
K' | 1.43 | 4.08 | 1.31 | 1.57 | 1.20 | |
Α | 1.93 | 1.03 | 1.58 | 1.73 | 1.03 | |
W | 0.81 | 0.71 | 0.19 | 0.15 | 0.23 | |
T | 3.2 | 1.6 | 1.3 | 1.7 | 1.8 | |
N | 607 | 1159 | 2820 | 1732 | 20,290 | |
Xylazine | RSDa | 0.64 | 3.41 | 1.91 | 0.23 | 0.40 |
Rs | DNA | DNA | DNA | DNA | DNA | |
LOD (pgoncolumn) | 0.30 | 0.09 | 0.50 | 0.50 | 0.0038 | |
K' | 2.77 | 6.65 | 2.08 | 2.72 | 1.16 | |
Α | DNA | DNA | DNA | DNA | DNA | |
W | 1.71 | 1.04 | 0.29 | 0.36 | 0.17 | |
T | 3.9 | 2.8 | 1.3 | 2.5 | 1.6 | |
N | 287 | 1232 | 2054 | 612 | 7988 |